Mortierella wolfii–Associated Invasive Disease

Mortierella wolfii–Associated Invasive Disease

a 34-year-old man was admitted because of severe shock to the intensive care unit (ICU) at University Hospital of Liege (Liege, Belgium) on day 10 after nonfamilial hematopoietic stem cell transplantation (HSCT). X-linked gp91phox gene mutation chronic granulomatous disease (CGD) had been diagnosed when he was 4 years of age. The patient had a history of recurrent pulmonary aspergillosis (Asper...

Sesamin inhibits lysophosphatidylcholine acyltransferase in Mortierella alpina.

The filamentous fungus, Mortierella alpina, accumulates complex lipids relatively rich in arachidonic acid (C(20:4) Delta(5,8,11,14)). The lignan, sesamin, has been used to reduce arachidonic acid production by specifically inhibiting Delta(5)-desaturation [Shimizu, Akimoto, Shinmen, Kawashima, Sugano and Yamada (1991) Lipids 26, 512-516]. Microsomal membrane preparations from M. alpina exhibit...

Invasive pneumococcal disease.

INTRODUCTION Streptococcus pneumoniae, the pneumococcus, is a Gram-positive diplococcus with more than 90 serotypes determined by the polysaccharide composition of its capsule. It is carried asymptomatically in approximately 50% of people.1 It can cause both non-invasive and invasive disease. Invasive pneumococcal disease (IPD) refers to disease in which the bacterium enters a sterile site such...

Invasive meningococcal disease in childhood.

Surveillance of Invasive Meningococcal Disease

Invasive meningococcal disease (IMD) is a nationally reportable disease in Canada. Since 1985, the Laboratory Centre for Disease Control (LCDC) has enhanced IMD surveillance to correlate case-by-case information provided by the provinces and territories with detailed laboratory studies done at the National Laboratory for Bacteriology at LCDC. This report provides information on IMD from 1 Janua...